红细胞痛
医学
表型
神经病理性疼痛
感觉系统
神经科学
感觉神经病变
皮肤病科
麻醉
生物
遗传学
内科学
基因
作者
Lishuang Cao,Aoibhinn McDonnell,Anja Nitzsche,Aristos J. Alexandrou,Pierre-Philippe Saintot,Alexandre Loucif,Adam R. Brown,Gareth T. Young,Malgorzata A. Mis,Andrew D. Randall,Stephen G. Waxman,P Stanley,Simon Kirby,Sanela Tarabar,Alex Gutteridge,Richard P. Butt,Ruth M. McKernan,Paul J. Whiting,Zahid Ali,James Bilsland,Edward B. Stevens
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2016-04-20
卷期号:8 (335)
被引量:156
标识
DOI:10.1126/scitranslmed.aad7653
摘要
A selective Nav1.7 sodium channel blocker reduced hyperexcitability of iPSC-derived sensory neurons and alleviated pain in a subpopulation of patients with an inherited pain disorder.
科研通智能强力驱动
Strongly Powered by AbleSci AI