Objective To study clinical symptoms, indication's for operation and operative methods of the crohn's disease. Methods 22 cases of crohn's disease in our department from 1995-2000 years were presented. Results 22 cases patients clinical symptoms have intestinal obstuction, gastrointestinal hemorrhage, or intestinal leakage. All patients recept operative treatment. 2 patients died after emergency surgery because the patient's situation went wores. The other 20 patients were well. Conclusion Crohn's disease is a no specific chronic in-flammnation in digestive canal, and the non-operation treament also relieve symptone, but can not treatment well all. Therefor elect earlie operative is necessary.