The Effect of 10 % Lidocaine Spray on Hemodynamics and Postoperative Sore Throat Accompanied by Endotracheal Intubation

Background: Laryngoscopy and endotracheal intubation are potential stimuli that can frequently induce increased sympathetic activity and postoperative sore throat. The authors studied the effects of 10% lidocaine (Xylocaine 10% Spray, Astra, Sweden) spray on hemodynamic responses and postoperative sore throat after laryngoscopy and endotracheal intubation. Methods: Forty ASA 1 patients undergoing elective surgery were allocated randomly to two groups. Control group was intubated without 10% lidocaine spray. Study group was intubated with 10% lidocaine spray to pharyngolaryngeal(1 mg/kg) and intratracheal (l mg/kg) sites during the induction of anesthesia. Results: The results obtained were as follows. Compared with the control group, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure were significantly decreased in 10% lidocaine spray group. But the incidence of arrhythmia and an increase in heart rate were not different between two groups. Sore throat was more significantly less in 10% lidocaine spray group than the control group. Conclusions: The elevation of blood pressure, and the incidence of postoperative sore throat accompanied by endotracheal intubation can be prevented with 10% lidocaine spray to pharyngolaryngeal and intratracheal sites before intubation. (Korean J Anesthesiol 1996; 30: 663-667)