Screening Lead compounds of Herbicide from Microorganism with Arabidopsis thaliana

The germination and responses of Arabidopsis thaliana to conventional solvents were studied with agar-solution under artificial conditions. Arabidopsis thaliana and several targets were assayed for their responses to 2 commercial herbicide standards and 7 commercial herbicide products, and screened on 1 880 microbial extracts. The results showed that Arabidopsis thaliana was stable,highly efficient, simple and sensitive for screening lead compounds. The screening method with Arabidopsis thaliana could offer the multiple sieves to ensure that low active compounds would not be missed. Arabidopsis thaliana is one of the top choices of dicotyledons for screening lead compounds of herbicide.