Molecular mechanisms of copper homeostasis in the cells

Copper plays an essential role in normal human physiology.Copper misbalance affects body dysfunction,such as Menkes' and Wilson's disease.It is a key factor about the maintenance of the body and cell regulation of copper metabolism and copper homeostasis,related to the absorption,transport and removal of copper.Recent studies yielded new information on the function and regulation of human copper transporters,copper homeostasis and other metabolic pathways.The copper homeostasis regulation is emerging and perfecting.