脂肪性肝炎
脂肪肝
医学
脂肪变性
胰岛素抵抗
内分泌学
内科学
转录组
生物
疾病
癌症研究
胰岛素
生物化学
基因
基因表达
作者
Amon Asgharpour,Sophie C. Cazanave,Tommy Pacana,Mulugeta Seneshaw,Robert Vincent,Bubu A. Banini,Divya P. Kumar,Kalyani Daita,Hae-Ki Min,Faridoddin Mirshahi,Pierre Bédossa,Xiaochen Sun,Yujin Hoshida,Srinivas V. Koduru,Daniel Contaifer,Urszula Osinska Warncke,Dayanjan S. Wijesinghe,Arun J. Sanyal
标识
DOI：10.1016/j.jhep.2016.05.005
摘要
We have developed a diet-induced mouse model of non-alcoholic steatohepatitis (NASH) and hepatic cancers in a cross between two mouse strains (129S1/SvImJ and C57Bl/6J). This model mimics all the physiological, metabolic, histological, transcriptomic gene signature and clinical endpoints of human NASH and can facilitate preclinical development of therapeutic targets for NASH.
科研通智能强力驱动
Strongly Powered by AbleSci AI
PDF的下载单位、IP信息已删除
(2025-6-4)
invisight
Yinxb
DW
蓝天
xing_xing
aajhajkahna
aaaa
152455
OK
嘻嘻哈哈
pluto
林狗
科研狗
123
璐璐
乐空思
重要柠檬
七听
小时
小迪
皖公网安备34019202002308
