The motor function of the human stomach and starvation activity of dogs were investigated after their exposure to accelerations of various values and duration. Inhibition of the motor function of the stomach and alteration in the periodicity pattern were found. The alteration included suppression of hungry contractions, development of continuous motor activity and gradual recovery of periodic activity of the stomach. Motor changes were related to the acceleration value. The reaction of the motor apparatus of the stomach to accelerations was shown to be nonspecific. The changes in the motor function of the stomach seem to be secondary and to be associated with the changes in the functional state of regulatory centers of motor activity.