Study on chemical constituents from leaves of Naudea officinalis

To study the chemical constituents of the leaves of Naudea officinalis.The chemical constituents were separated by column chromatography and semi-preparative HPLC techniques, and their structures were determined by spectral analysis.Five compounds were isolated and identified as strictosamide (1), 10-hydroxy strictosamide (2), kaempferol-3-O-rutinoside (3), rutin (4), pumiloside(5).Among these compounds, 2, 3, 4 are isolated from the leaves of Naudea officinalis for the first time.