[Preliminary study on the role of IL-1β+ neutrophils in bone regulation of periodontitis mice].

IL-1β⁺ neutrophils are significantly increased in the diseased maxillary alveolar bone of mice with periodontitis, which inhibit the osteogenic differentiation of MC3T3-E1 cells and are associated with the TLR4-NF-κB signaling pathway, providing a scientific basis for immunotherapy for bone regeneration in periodontitis.