Porphyrin–palladium hydride MOF nanoparticles for tumor-targeting photoacoustic imaging-guided hydrogenothermal cancer therapy

A nanoscale porphyrin–palladium metal–organic framework (Pd-MOF) with highly dispersive Pd atoms as hydrogen carrier was developed to efficiently load highly reductive hydrogen for the tumor-targeted photoacoustic imaging (PAI)-guided hydrogenothermal therapy of cancer.