Scientific Rationale for Designing Controlled Drug Delivery Systems

Abstract The past few decades have seen giant investigations and observations in novel and controlled drug delivery systems. There are diverse operations that necessitate the generation of such systems that can control the release rate or delivery of drugs systemically thereby reducing the frequent dosing, improving the fluctuations in plasma levels, which in turn can lower the risk of unwanted side effects. In addition, they show better targeting. The ideal drug delivery system may deliver at a constant rate and can give a required therapeutic response. This chapter aims to describe the rationale involved in the fabrication of a controlled drug delivery system with emphasis on different approaches (physical, chemical, and biological) and properties of drug candidates.