Extracellular vesicles in immunomodulation and tumor progression

Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as mediators of communication between cancer and immune cells. This expanded role of EVs may shed light on the mechanisms behind tumor progression and provide translational diagnostic and prognostic tools for immunologists. Extracellular vesicles (EVs) can exert potent immunomodulatory effects. Wirtz and colleagues review the types of EV and their influence on tumor responses.