Aim. To reveal the peculiarities of biological age and age changes rate in athletes of playing kinds of sport and persons, not engaged in sports. Materials and methods. The study included 141 persons: athletes - 61 persons (men - 31, women - 30) and subjects, who do not go in for sports - 80 persons (men - 34, women - 46). All the participants were of period I mature age. Biological age and age changes rate were determine by anthropometric data. Results. Athletes of playing kinds of sport demonstrated lower biological age and slowed age changes rate in comparison with persons, who do not go in for sports. The biological age in the group of athletes was lower than the chronological one; the biological age in the group of persons, not engaged in sport, was higher than the chronological one. Conclusions. The study indicated a positive influence of systematic physical activity of playing kinds of sport on the processes of body ageing, namely, reduction of biological age and slowing of age changes rate. This kind of physical activity can be recommended to persons of mature age for formation of programs of optimal motor regimen.