Efficacy of Intravenous Iron in Cancer Patients with Moderate to Severe Iron Deficiency Anaemia

Introduction: Iron deficiency anaemia is common in patients with cancer. Intravenous iron is approved for treatment of iron deficiency anaemia when oral iron preparations are ineffective. Few data are available on the rapidity of haemoglobin correction in patients with cancer and moderate to severe iron deficiency anaemia who are given intravenous iron. Methods: We retrospectively reviewed the efficacy and safety of ferric carboxymaltose (FCM) in cancer patients with iron deficiency anaemia who were treated in our centre from January to June 2019. The primary endpoint was the rise in haemoglobin levels at day 7, day 14, and day 28 after the first dose of FCM. The secondary endpoints included the change in iron profile, the sustainability of haemoglobin response at day 60, and the changes in patients' transfusion requirements following FCM.