Obesity as an important risk factor for certain types of cancer.

医学 肥胖 癌症 子宫内膜癌 结直肠癌 前列腺癌 风险因素 胰腺癌 疾病 内科学 乳腺癌 入射(几何) 遗传 癌症预防 肿瘤科 物理 光学 生物 遗传学
作者
Sayed Hossein Davoodi,Talieh Malekshahabi,Ali Malekshahi-Moghadam,Roghieh Shahbazi,Saeideh Esmaeili
出处
期刊:PubMed [National Institutes of Health]
卷期号:6 (4): 186-94 被引量:52
标识
摘要

Cancer could be described as the uncontrolled and unrestricted growth of malignant cells in any place of the body. It is a multifactorial disease which either heredity or environmental factors (such as nutrition, physical inactivity, alcohol, obesity, exposure to sun, environmental pollutants, infections) chip in incidence of cancer. In recent years, several researchers have focused on obesity as a potent cancer risk factor. Scientificevidences have suggested that obesity has associated with increased risk for a plenty of different types of cancer. The evidences are the most consistent for endometrial cancer, breast cancer between the postmenopausal women, and renal cell cancer. More contradictoryresults have reported about the colorectal, prostate, and pancreatic cancer. Although numerous studies have done according to the obesity and cancer relation or joint, but the molecular mechanisms in which obesity could increase the risks of cancer, have been poorly understood.

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