An Improved Bonferroni Procedure for Multiple Tests of Significance
作者
R. John Simes
出处
期刊:Biometrika [Oxford University Press] 日期:1986-12-01卷期号:73 (3): 751-751被引量:157
标识
DOI:10.2307/2336545
摘要
A modification of the Bonferroni procedure for testing multiple hypotheses is presented. The method, based on the ordered p-values of the individual tests, is less conservative than the classical Bonferroni procedure but is still simple to apply. A simulation study shows that the probability of a type I error of the procedure does not exceed the nominal significance level, α, for a variety of multivariate normal and multivariate gamma test statistics. For independent tests the procedure has type I error probability equal to α. The method appears particularly advantageous over the classical Bonferroni procedure when several highly-correlated test statistics are involved.