比例危险模型
统计
危害
累积发病率
估计员
计量经济学
回归分析
比例(比率)
事件(粒子物理)
加性模型
一致性(知识库)
数学
计算机科学
有机化学
物理
化学
队列
量子力学
几何学
作者
Minjung Lee,Jason P. Fine
摘要
In the analysis for competing risks data, regression modeling of the cause‐specific hazard functions has been usually conducted using the same time scale for all event types. However, when the true time scale is different for each event type, it would be appropriate to specify regression models for the cause‐specific hazards on different time scales for different event types. Often, the proportional hazards model has been used for regression modeling of the cause‐specific hazard functions. However, the proportionality assumption may not be appropriate in practice. In this article, we consider the additive risk model as an alternative to the proportional hazards model. We propose predictions of the cumulative incidence functions under the cause‐specific additive risk models employing different time scales for different event types. We establish the consistency and asymptotic normality of the predicted cumulative incidence functions under the cause‐specific additive risk models specified on different time scales using empirical processes and derive consistent variance estimators of the predicted cumulative incidence functions. Through simulation studies, we show that the proposed prediction methods perform well. We illustrate the methods using stage III breast cancer data obtained from the Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute.
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