Carbonylation ofC(sp3)XBonds UtilizingCO

The transition metal catalyzed Csp 3 carbonylation is becoming a more and more important tool to synthesize kinds of aliphatic carbonyl-containing derivatives. The CO molecule could be introduced into the organic molecules as a vital functional group. In this chapter, we review the transition-metal-catalyzed carbonylation of Csp 3 compounds. Various β,γ-unsaturated carbonyl compounds, aliphatic carboxylic acid, and their derivatives could be achieved from allylic compounds, benzyl compounds, aliphatic compounds, etc. Finally, we summarize the current progress in the Csp 3 carbonylation and look forward its development.