睾丸癌
医学
生殖细胞肿瘤
生殖细胞
精原细胞瘤
睾丸生殖细胞瘤
内科学
癌症
肿瘤科
化疗
细菌
癌症研究
睾丸切除术
胚胎癌
作者
Ana Koši Kunac,Milena Gnjidić,Zrna Antunac Golubić,Marija Gamulin
出处
期刊:Acta Clinica Croatica
[Sestre Milosrdnice University Hospital Center (KBC Sestre milosrdnice)]
日期:2020-09-01
卷期号:59 (3): 496-504
标识
DOI:10.20471/acc.2020.59.03.14
摘要
Germ-cell testicular cancer (GCTC) is a malignant neoplasm derived from the primordial germ cell. Although it accounts for approximately 1% of all malignancies in men, it is the most common cancer of younger male population, with the highest incidence between ages 15 and 35. Testicular cancer incidence rate has risen globally over the past several decades, with the average increase in the incidence of testicular cancer in Croatia of 7% per annum from the year 1983 to 2007. Two main groups are seminomas and non-seminomas, each accounting for 50% of cases, and they differ in treatment modalities and response to therapy. Despite increase in the incidence rate, a promising circumstance is that GCTC has become a model of curable cancer. Because of advances in diagnostic procedures, sophisticated radiation techniques and especially the introduction of cisplatin based chemotherapy protocols together with advanced postchemotherapy surgical techniques, curability is expected in about 95% of all patients diagnosed with testicular cancer and over 70% of patients with advanced disease. In this review, we will focus on treatment strategies of primary GCTC.
科研通智能强力驱动
Strongly Powered by AbleSci AI