拟杆菌
细胞外小泡
拟杆菌
分离(微生物学)
微生物学
细菌
生物
细胞外
细胞生物学
遗传学
作者
Régis Stentz,Ariadna Miquel-Clopés,Simon R. Carding
出处
期刊:Methods in molecular biology
日期:2021-11-17
卷期号:: 171-190
被引量:2
标识
DOI:10.1007/978-1-0716-1900-1_11
摘要
Bacterial extracellular vesicles (BEVs) possess features that make them well suited for the delivery of therapeutics and vaccines. This chapter describes methods for engineering the commensal human intestinal bacterium Bacteroides thetaiotaomicron (Bt) to produce BEVs carrying vaccine antigens and accompanying methods for isolating and purifying BEVs for mucosal vaccination regimens.
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