生物
黄芪
病毒学
多糖
免疫系统
免疫
斑马鱼
微生物学
先天免疫系统
免疫学
生物化学
医学
基因
病理
中医药
替代医学
作者
Yu Li,Chao Ran,Kaijian Wei,Yadong Xie,Mingxu Xie,Wei Zhou,Yalin Yang,Zhen Zhang,Huiyuan Lv,Xufa Ma,Zhigang Zhou
出处
期刊:Aquaculture
[Elsevier]
日期:2021-07-15
卷期号:540: 736677-736677
被引量:17
标识
DOI:10.1016/j.aquaculture.2021.736677
摘要
Abstract Our study aimed to investigate the effect of dietary Astragalus polysaccharide (APS) on growth performance, gut and liver health and anti-viral capability of zebrafish. Zebrafish were fed control diet and the experimental diets containing 0.01% or 0.02% APS for three weeks. Growth performance, gut health parameters such as expression of inflammatory and tight junction genes, antioxidant capability, and microbiota composition were detected after three weeks feeding. Liver health was evaluated by serum ALT and AST levels, as well as expression of genes realated to inflammation and lipid metabolism. Zebrafish were challenged by SVCV at the end of feeding. The antiviral immune response was evaluated at 4 days post SVCV infection and survival rate was calculated 14 days after challenge. The results showed that 0.01% and 0.02% APS supplementation increased weight gain and decreased the FCR of zebrafish (P
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