转录组
生物
心肌梗塞
免疫学
骨髓
内科学
粒细胞生成
细胞生物学
医学
造血
基因表达
干细胞
基因
生物化学
作者
Ehsan Vafadarnejad,Giuseppe Rizzo,Laura Krampert,Panagiota Arampatzi,Paula-Anahi Arias-Loza,Yara Nazzal,Anna Rizakou,Tim Knochenhauer,Sourish Reddy Bandi,Vallery Audy Nugroho,D. Schulz,Melanie Roesch,Paul Alayrac,José Vilar,Jean‐Sébastien Silvestre,Alma Zernecke,Antoine‐Emmanuel Saliba,Clément Cochain
出处
期刊:Circulation Research
[Lippincott Williams & Wilkins]
日期:2020-08-19
卷期号:127 (9): e232-e249
被引量:244
标识
DOI:10.1161/circresaha.120.317200
摘要
Altogether, our data provide a time-resolved census of neutrophil diversity and gene expression dynamics in the mouse blood and ischemic heart at the single-cell level, and reveal a process of local tissue specification of neutrophils in the ischemic heart characterized by the acquisition of a SiglecFhi signature.
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