纳米载体
光学透明度
生物利用度
药物输送
纳米技术
材料科学
乳状液
透明度(行为)
生化工程
药品
计算机科学
化学
药理学
医学
工程类
生物化学
计算机安全
光电子学
作者
Lovelyn Charles,Anthony A. Attama
出处
期刊:Journal of Biomaterials and Nanobiotechnology
[Scientific Research Publishing, Inc.]
日期:2011-01-01
卷期号:02 (05): 626-639
被引量:309
标识
DOI:10.4236/jbnb.2011.225075
摘要
Nanoemulsions have attracted great attention in research, dosage form design and pharmacotherapy. This is as a result of a number of attributes peculiar to nanoemulsions such as optical clarity, ease of preparation, thermodynamic stability and increased surface area. Nanoemulsions also known as submicron emulsions serve as vehicles for the delivery of active pharmaceutical ingredients as well as other bioactives. They are designed to address some of the problems associated with conventional drug delivery systems such as low bioavailability and noncompliance. The importance of design and development of emulsion nanocarrier systems aimed at controlling and/or improving required bioavailability levels of therapeutic agents cannot be overemphasized. Reducing droplet sizes to the nanoscale leads to some very interesting physical properties, such as optical transparency and unusual elastic behaviour. This review sheds light on the current state of nanoemulsions in the delivery of drugs and other bioactives. The morphology, formulation, characteristics and characterization of nanoemulsions were also addressed.
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