脂肪组织
结缔组织
白色脂肪组织
生物
前体细胞
祖细胞
细胞生物学
内皮干细胞
电池类型
3T3-L1
干细胞
体外
细胞
内分泌学
脂肪细胞
遗传学
出处
期刊:The anatomical record
[Wiley]
日期:1987-12-01
卷期号:219 (4): 331-337
被引量:27
标识
DOI:10.1002/ar.1092190402
摘要
Abstract Studies on the development of brown and white adipose: tissues and their relationship to ordinary connective tissue are the subject of the present review, which is updated to the fall of 1985. Primordial entities described as “primitive organs” have been noted at sites of adipose tissue development by numerous investigators. These “primitive organs” are clearly delineated from surrounding connective tissue and possess a well‐defined vascular network in the interstices of which cellular organization takes place. The precursor cells of brown and white adipocytes appear to acquire their distinctive cytogenetic properties at a very early stage in the embryo. These progenitor cells temporarily exhibit structural similarities to fibroblasts and endothelial cells. This resemblance has led to speculation that fibroblasts and/or endothelial cells may be ancestral to adipocytes. However, recent in vivo and in vitro observations suggest that the brown adipose precursor cell is morphogenetically distinct from the white adipose precursor cell on one hand, and from fibroblasts and endothelial cells on the other. In vitro studies have also shown that the pericytic elements present in both brown and white adipose tissue depots in the adult are quiescent precursor cells that may be recruited under certain circumstances. Areas for further inquiry by means of recently developed techniques are indicated.
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