Objective:To improve the radical resection rate of pancreatic head cancer that involving the Portal Vein (PV) and Superior Mesenteric Vein (SMV).Methods:11 cases,including those with the involvement of PV/SMV,were performed extended pancreaticoduodenectomy.Results:8 of the 11 cases were performed partial resection of the wall of blood vessels.The other 3 cases got segment resection of the blood vessel.No embolization,intestinal necrosis or hepatic failure were found in the whole group.No death or recurrence were found in the short time follow up.Conclusion:It is feasible to perform with extended pancreaticoduodenectomy accompanied with involvement of PV/SMV for those with pancreatic head carcinoma.