化学
抗菌剂
部分
吡啶
亲核细胞
试剂
组合化学
细胞毒性
有机化学
生物化学
体外
催化作用
作者
Mahmoud A. A. El-Remaily,Omar M. Elhady,Eman Abdelraheem
摘要
In an attempt to find a new class of antimicrobial agents, a series of pyridoxazepine, pyridothiazepine, triazepine, naphthyridine, pyridopyrimidine, and other related products containing pyridine moiety were synthesized via the reaction of 2-amino-6-chloro-3,5-dicyanopyridine 1 with nucleophilic chemical reagents. These compounds were screened for cytotoxicity and their antimicrobial activity. Most of products showed inhibitory effect.
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