Type Detection and Analysis of Human Papillomavirus in 1 619 Patients with Condyloma Acuminatum

Objective To investigate human papillomavirus(HPV) genotype in patients with condyloma acuminatum(CA) in Shenzhen.Methods HPV genotype was detected with human papillomavirus genotyping kit in 1 619 patients with CA.Results The ratio of low-risk HPV type(LRHT) and high-risk HPV type(HRHT) were 68.6% and 57.3% in 1 619 patiets with CA respectively.Main HPV genotypes were 6(35.8%),11(25.1%),43(14.8%),16(14.5%),52(10.1%),58(8.3%) and 18(5.7%).There were statistically significant difference on HRHT positive rate between male and female(P 0.01).The positive rate of the single type HPV infection was 63.9%,and the positive rate of multiple type HPV infection was 36.1%.The ratio of HRHT mixed infection was 89.7%(524/584)in multiple type HPV infection.There was statistically significant difference on multiple type infection between male and female(P0.001).Conclusion LRHT(HPV6,11,43) is main HPV infection type in Shenzhen,but HRHT(HPV16,52,58,18) is increasing.HRHT mainly exists by a way of mixed infection,and female patients are easier to be infected by multiple HPV type.