Effects of Different Purification Methods on Content of Caffeoyl Quinic Acids from Flos Lonicerae Extractive

Objective:To study the effects of different purification ways on the extractive rate of caffeoyl quinic acids in Flos Lonicerae extractive.Method:Several purification processes were used respectively in the preparation of Flos Lonicerae extractive,such as alcohol precipitation method,lime-sulfur method,lime-sulfur ethanol method,macroporous resin method,and extraction method etc.The content of the six caffeoyl quinic acids was determined by HPLC.Result:The content of the caffeoyl quinic acids in Flos Lonicerae extractive by extraction method was higher than the other methods.Total content of caffeoyl quinic acids was up to 83.91%.Conclusion:The extraction method is the best in the preparation of Flos Lonicerae extractive.