Chronic diarrhea is defined as the diarrhea symptom persisting for more than 4 weeks.A practical and widely used approach for its diagnosis is based on the stool characteristics,that is watery,inflammatory,or fatty in nature (steatorrhea).The decision-making strategy for pursuing the etiology of chronic diarrhea outlined is based on the stool characteristics,and the diagnosis and management of chronic diarrhea of obscure origin have also been discussed.