Study on ganodema acid extracted from Ganoderma lucidum by ultrasound

Objective:The extraction process of ganoderma acid from Ganoderma lucidum mycelia by ultrasound was studied.Methods:Unit Ganoderma lucidum mycelia of ganoderma acid as the indicator,using single-factor analysis and orthogonal experiment,the effects of ethanol concentration,ultrasonic extraction time,extraction pH and solid-liquid ratio on ganoderma acid from Ganoderma lucidum mycelia was studied.Results:The optimum extraction conditions were 100% ethanol concentration,ultrasonic extraction time 90min,pH2.5,plus 12 times the amount of ethanol,content of ganoderma acid was up to 46.7mg·g-1.Conclusion:Extraction using ultrasonic technology can greatly improve the extraction yield of Ganoderma lucidum comparing with conventional method,and shorten the extraction time.