Objective To study new assay fulfill the repuive ments for diagnostic exclusinm in patients supected of pulmonary embolism.Methods Plasma D-dimer of dini cally suspected Pul monary embolism patients were measured by VIDAS D-Dimer,one year after their in dusion all patients were con firmed to know if they had any new symptoms suggestive of deep vein thrombosis or pulmonary embolism.Results Among 104 suspected pulmonary embolism patients,32 patients with DD levels494 ng/ml and 72 patients with DD levels494 ng/ml,16 patients were one of them with DD levels494 ng/ml,the test showed a sensitivity of 100%,a negative predictive vale of 100%.Conclusion VIDAS D-dimer is well sited asdiagnostic tool for the exdusion Pulmonary embolism.