The clinical values of BuChE and PA and Alb Assay in diagnosis and prognosis of cirrhosis

Objective:To evaluate the clinical values of BuChE and PA and Alb Assay in diagnosis and prognosis of cirrhosis. Methods:To measure the activity of BuChE and the concentration of PA and Alb in serum of 197 patients with cirrhosis. The sensitivity and specificity and other performances of BuChE and PA and Alb assay for the detection of cirrhosis were evaluated by ROC curve analysis. Results: The activity of BuChE and the concentration of PAand Alb in serum of 197 patients with cirrhosis are lower than the control group(P0.01). There are singnificant difference between Child-Pough A and Child-Pough B Child-Pough C, each grade and the control group(P0.01). The activity of BuChE and concentration of PA are positive correlation to the concentration of Alb in the patients with cirrhosis. Conclusions: The serum BuChE and PA are better than Alb in the diagnosis and prognosis of cirrhosis.