The thermal compression flow stress behavior of the hot compression deformation of Ti62421s alloy with reduction rate of 60% was studied under the deformation temperature range of 900-1 060 ℃ and strain rate range of 0.001-10 s-1.The effect of temperature and strain rate on hot deformation flow stress of Ti62421s was studied,and the constitutive model equations and processing maps of hot deformation flow stress of Ti62421s alloy were established.The results show that during hot compression process,the flow stress increases with the increase of strain,then gradually stabilizes after reaching peak stress.The phenomenon of discontinuous yielding appears under the high strain rate(10 s-1) deformation;the peak stress increases with the increase of strain rate and decreases with the increase of temperature;and the optimal deformation process parameters of the alloy are as follows: temperature is 980 ℃,strain rate is 0.01-0.1 s-1.