Reducing the global burden of depression: a Lancet–World Psychiatric Association Commission

Depression is the leading cause of mental health-related disease burden globally, affecting an estimated 300 million people worldwide. 1 Patel V Chisholm D Parikh R et al. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition. Lancet. 2016; 387: 1672-1685 Summary Full Text Full Text PDF PubMed Scopus (408) Google Scholar It represents a barrier to sustainable development in all regions. 2 Lund C Brooke-Sumner C Baingana F et al. Social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews. Lancet Psychiatry. 2018; 5: 357-369 Summary Full Text Full Text PDF PubMed Scopus (316) Google Scholar Depression prevents people from reaching their full potential, impairs human capital, and is associated with premature mortality from suicide and other illnesses. 1 Patel V Chisholm D Parikh R et al. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition. Lancet. 2016; 387: 1672-1685 Summary Full Text Full Text PDF PubMed Scopus (408) Google Scholar