溃疡性结肠炎
医学
结肠炎
胃肠病学
内科学
炎症性肠病
金标准(测试)
直肠
疾病
作者
Elisabetta Antonelli,Vincenzo Villanacci,Gabrio Bassotti
标识
DOI:10.3748/wjg.v24.i47.5322
摘要
Ulcerative colitis (UC), a chronic, relapsing, remitting disease of the colon and rectum, is characterized by inflammatory ulceration of the mucosa.Current UC therapy relies on controlling acute episodes and preventing relapse.To predict modifications in the natural course of UC, mucosal healing (MH) has emerged as a major treatment goal.Endoscopic evaluation is considered the gold standard for assessing MH, which can be achieved by conventional drugs and biologics in many, but not all, patients.Consequently, interest is focusing on the development of new substances for UC therapy, and new oral agents are in the pipeline.This review will focus on the ability of newly developed oral drugs to induce and maintain MH in UC patients.
科研通智能强力驱动
Strongly Powered by AbleSci AI