Urticarial vasculitis and associated disorders

Patients often present to allergists with urticarial eruption symptoms. In many instances, these lesions represent chronic idiopathic or spontaneous urticaria. [1] Krishnaswamy G. Youngberg G. Acute and chronic urticaria. Challenges and considerations for primary care physicians. Postgrad Med. 2001; 109 (119): 107-108 Crossref PubMed Scopus (18) Google Scholar Some of these patients may have a condition referred to as urticarial vasculitis (UV), including its variants normocomplementemic urticarial vasculitis (NUV), hypocomplementemic urticarial vasculitis (HUV), and hypocomplementemic urticarial vasculitis syndrome (HUVS) or Schnitzler syndrome. 2 Zuberbier T. Maurer M. Urticarial vasculitis and Schnitzler syndrome. Immunol Allergy Clin North Am. 2014; 34: 141-147 Abstract Full Text Full Text PDF PubMed Scopus (16) Google Scholar , 3 Guha B. Youngberg G. Krishnaswamy G. Urticaria and urticarial vasculitis. Compr Ther. 2003; 29: 146-156 Crossref PubMed Google Scholar There are some features that set this condition apart, and in some instances, the disease may be severe enough to require systemic immunosuppressive therapies. UV, Schnitzler syndrome, and related disorders are discussed in this review. Urticarial vasculitis and autoimmune thyroid disease: Do we have enough data?Annals of Allergy, Asthma & ImmunologyVol. 120Issue 1PreviewWe read the original article, “Urticarial vasculitis and associated disorders,” by Hamad et al.1 In this noteworthy article, the investigators stated that several autoantibodies, including antimicrosomal antibodies, might be detected in patients with hypocomplementemic urticarial vasculitis (HUV) and HUV syndrome, 2 variants of urticarial vasculitis (UV). They provided 2 references to support this statement. We searched for these 2 references and deeply explored the medical literature, and we could not find a conclusive source to confirm or deny that microsomal antibodies are present in UV. Full-Text PDF