化学
受体酪氨酸激酶
酪氨酸激酶
药理学
AXL受体酪氨酸激酶
酪氨酸激酶抑制剂
癌症治疗
癌症
受体
生物化学
癌症研究
内科学
JAK-STAT信号通路
医学
生物
作者
Dillon H. Miles,Manjunath Lamani,Srinivas Reddy Paladugu,Shiwei Qu,Corinne N. Foley,Ehesan U. Sharif,Joice Thomas,Pradeep Nareddy,Joel W. Beatty,Balint Gal,Guiling Zhao,Rebecca Grange,Stefan G. Shaqfeh,Ada Chen,Hema Singh,Yue Tong Lee,Xiaoning Zhao,David Green,Hsin‐Ting Huang,Elaine Ginn
标识
DOI：10.1021/acs.jmedchem.5c00239
摘要
studies, AB801 was recently dosed in healthy volunteers and is currently being evaluated clinically as a single agent in advanced solid tumors and in combination with chemotherapy for the treatment of nonsmall cell lung cancer (NSCLC).
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(2025-6-4)
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