转移
癌症研究
免疫系统
免疫学
免疫
医学
癌症
内科学
作者
Ahmad Mustafa Shiri,Tao Zhang,Tanja Bedke,Dimitra E. Zazara,Lilan Zhao,Jöran Lücke,Morsal Sabihi,Antonella Fazio,Siwen Zhang,Daniele V. F. Tauriello,Eduard Batlle,Babett Steglich,Jan Kempski,Theodora Agalioti,Mikołaj Nawrocki,Yang Xu,Kristoffer Riecken,Imke Liebold,Leonie Brockmann,Leonie Konczalla
标识
DOI：10.1016/j.jhep.2023.12.015
摘要
The liver is one of the organs most commonly affected by metastasis. The presence of liver metastases has been reported to be responsible for an immunosuppressive microenvironment and diminished immunotherapy efficacy. Herein, we aimed to investigate the role of IL-10 in liver metastasis and to determine how its modulation could affect the efficacy of immunotherapy in vivo.
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