环加成
催化作用
戒指(化学)
组合化学
金属
Atom(片上系统)
化学
反应条件
有机化学
计算机科学
并行计算
作者
Kostiantyn O. Marichev
出处
期刊:Topics in heterocyclic chemistry
日期:2023-01-01
卷期号:: 187-223
摘要
The synthesis of heterocyclic compounds via catalytic cycloaddition reactions of metallocarbenes is robust, atom-economic, and often allows access to chiral heterocycles with high levels of stereocontrol. This methodology has demonstrated advantages over other metal- and organo-catalytic approaches towards heterocycles (e.g., lower catalyst loading, use of inexpensive metal catalysts, mild reaction conditions, excellent stereoselectivities, etc.). This chapter is comprehensive, and covers all available literature reports on cycloaddition using metallocarbenes to produce different ring size heterocycles: from small strained tri-membered to medium-size eight-membered rings.
科研通智能强力驱动
Strongly Powered by AbleSci AI