3-Methoxythiophene-Based Indophenine Reaction Generating an Isomeric Dynamic Equilibrium System

A 3-methoxythiophene-based indophenine reaction with N-(2-hexyldecyl)isatin in the presence of concentrated sulfuric acid produces an indophenine cis-trans isomeric dynamic equilibrium system, which is dominated by the (Z,E,Z) configuration with a trace of the (Z,Z,Z) configuration.