A new anthraquinone derivative from the marine fish-derived fungus Alternaria sp. X112

AbstractA new anthraquinone, altermodinacid A (1), and five known derivatives, pachybasic acid (2), emodic acid (3), emodin (4), phomarin (5), and 1,7-dihydroxy-3-methylanthracene-9,10-dione (6), were discovered from a halotolerant fungus Alternaria sp. X112 isolated from a marine fish Gadus macrocephalus. Their structures were determined by analysing MS and NMR data. The cytotoxic effect, antiagricultural pathogens activity, antibacterial activity and quorum sensing inhibitory potential of new compound 1 were evaluated.Keywords: Marine-derived fungusnatural productsanthraquinonesbioactivities Disclosure statementNo potential conflict of interest was reported by the authors.Additional informationFundingThis work was supported by the National Natural Science Foundation of China [grant numbers 41706077 and 81903494].