Glioblastoma multiforme in a mature ovarian teratoma with recurring brain tumours

Aims We report a case study to highlight the occurrence of glioblastoma multiforme in an ovarian teratoma. Methods and results A 10‐year‐old girl presented with a left frontal lobe primitive neuroectodermal tumour which was successfully treated. After 6 uneventful years, she developed glioblastoma multiforme located posterior to the site of the initial tumour. Six years later, she presented with a mature cystic teratoma containing glioblastoma multiforme. Conclusions Glioblastoma in an ovarian teratoma is an exceptional event, which might have an initial clinical presentation as a metastatic brain tumour. Alternatively, recurring glial tumours may occur in a genetically predisposed person; the role of radiation and chemotherapy in this context remains to be elucidated.