Efficient Solvent‐Free Syntheses of [2]‐ and [4]Rotaxanes

Waste not want not: A [2]rotaxane has been generated in 49 % yield through the direct grinding of solid macrocyclic, threadlike, and stoppering components. The same solid-state ball-milling reactions of solids of pseudorotaxanes and stoppers produced both [2]- and [4]rotaxanes in high yield (see picture). The approach relies on solid-state condensations and is convenient and waste-free (water is the only by-product). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z800530_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.