A Simple Preparation of Five-Carbon Chiral Allylic and Homoallylic Alcohol Synthons

All articles of this category Five-carbon homoallylic and allylic alcohols 4 , 5 , and 6 , potentially useful building blocks for the syntheses of a wide variety of optically active compounds, are prepared from chiral ( S )- O -benzylglycidol ( 1 ) via the selective formation of the terminal and internal acetylenic intermediates 2 and 3 .