Effects of Polymorphisms in ABCG2 , SLCO1B1 , SLC10A1 and CYP2C9 / 19 on Plasma Concentrations of Rosuvastatin and Lipid Response in Chinese Patients

These findings suggest that the increased plasma concentrations of rosuvastatin in Chinese patients are associated with increased lipid-lowering effects and lower doses of rosuvastatin should be effective in subjects with the ABCG2 421C>A variant.