Mechanistic insights into dietary CuO nanoparticles (CuO NPs)-induced hepatic lipotoxicity: The critical role of the Ccs/Mek1/Erk1/2/Pparα pathway and mitochondrial oxidative stress

Copper oxide nanoparticles (CuO NPs) are widely used in industry and agriculture, leading to their persistent occurrence and accumulation in aquatic environments and posing potential environmental risks. However, the specific...