Potential Phytoconstituents of Genus Vitex for the Management of Rheumatoid Arthritis: A Review

Rheumatoid arthritis is one of the most predominant conditions which have utmost influence on the society. The disease is an inflammatory disorder which affects joints, connective tissues, muscles, tendons and fibrous tissues. Approximately 270 known species of vitex genus are known, extending from shrubs to trees in the tropical, sub-tropical regions and temperate zones. Several species of vitex have been used traditionally over world-wide. The main focus of the present study is to review various phytoconstituents isolated from the genus vitex which can be used for the treatment of rheumatic disorders. The study also covers the underlying targets of the phytoconstituents which can be possible potential hits for the management of Rheumatic disorders.