放射性骨坏死
医学
头颈部
放射治疗
病因学
并发症
模式
入射(几何)
外科
普通外科
病理
社会科学
光学
物理
社会学
作者
Annu Singh,Joseph M. Huryn,Kenneth L. Kronstadt,SaeHee K. Yom,Joseph R. Randazzo,Cherry L. Estilo
标识
DOI:10.3389/froh.2022.980786
摘要
Osteoradionecrosis (ORN) of the jaw is one of the most dreaded complications of head and neck radiation therapy. Despite the evolution of radiation treatment modalities, ORN continues to remain a therapeutic challenge and its etiopathogenesis still remains unclear. It is clinically characterized by exposed necrotic bone within the head and neck radiation field. Over the past years, several studies have reported on the definition, staging, incidence, etiology, and management of this oral complication. In this review, we summarize the literature on ORN and discuss our institutional experience and management strategies that aim to predict and mitigate risk for ORN.
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