阿兹平
立体中心
化学
全合成
戒指(化学)
立体化学
形式综合
对映选择合成
有机化学
催化作用
作者
Xifei Yan,Qin Zhang,Jianfeng Zheng,Wei‐Dong Z. Li
标识
DOI:10.1021/acs.joc.4c00035
摘要
Formal total syntheses of stemonamine and cephalotaxine bearing the core cyclopenta[1,2-b]pyrrolo[1,2-a]azepine ring skeleton were achieved. The general synthetic strategy in the synthesis features the reductive oxy-Nazarov cyclization as key step, leading to the versatile construction of N-substituted spiro quaternary stereogenic centers from readily available starting materials.
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