bHLH130 mediates gibberellin signaling to regulate tanshinone biosynthesis in Salvia miltiorrhiza

on tanshinone accumulation. Collectively, our data propose that the bHLH130‒DELLA4 interaction constitutes a critical regulatory node, balancing GA signaling with secondary metabolite production and offering novel strategies for the metabolic engineering of tanshinones. In conclusion, this research delineates the regulatory role of bHLH130 in tanshinone synthesis, providing valuable insights into the GA-mediated modulation of secondary metabolism.